“It’s typical to see CFS 4–6 months after Covid,” Ostrosky-Zeichner said. “To find out if a patient has chronic fatigue syndrome, it’s a diagnosis of exclusion.”

Ostrosky-Zeichner said he would first rule out any acute complications and damage from COVID in his patients before making a long COVID diagnosis.

He explained that some people may experience heart or lung damage from COVID, while others may have underlying health conditions exacerbated by the virus.

“When we can’t find anything, we conclude it’s long COVID,” Ostrosky-Zeichner said.

Barshikar explained the cause of long COVID and chronic fatigue syndrome “involves a triggering challenge to the immune system from the viral infection.” He noted that both conditions are common in females.

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